Corneal ulcer after Insulin in dogs

The FDA has received 36 reports of corneal ulcer in dogs after Insulin. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

36Reports

72%Marked serious

31%Recovered

31%Died or euthanised

43 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

1 5.3%

3–7 days

2 11%

1–4 weeks

2 11%

Over a month

12 63%

How the animals did

Recovered

6 17%

Recovered with lasting effects

5 14%

Still unwell when reported

8 22%

Died

5 14%

Euthanised

6 17%

Not known

6 17%

Problems reported at the same time

Didn't work as expected

16 44%

Death

11 31%

Eye or vision problems

11 31%

Loss of appetite

9 25%

Ocular discharge

7 19%

Corneal disorder

7 19%

Cataract

6 17%

Lethargy

6 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause corneal ulcer in dogs?: 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 43 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Corneal ulcer with similar medicines

Corneal ulcer after Trilostane (Vetoryl) 54 reports · 0.5% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with corneal ulcer