Low sodium-potassium ratio (na:k ratio) after Gabapentin in dogs

43 reports to the FDA describe low sodium-potassium ratio (na:k ratio) in dogs given Gabapentin. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports

56%Marked serious

4.7%Recovered

9.3%Died or euthanised

82 daysTypical onset

How soon it started

Same day

1 4.0%

1–2 days

1 4.0%

3–7 days

0 0.0%

1–4 weeks

5 20%

Over a month

18 72%

How the animals did

Recovered

2 4.7%

Still unwell when reported

19 44%

Died

2 4.7%

Euthanised

2 4.7%

Not known

18 42%

Problems reported at the same time

34 79%

20 47%

17 40%

13 30%

13 30%

13 30%

10 23%

7 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause low sodium-potassium ratio (na:k ratio) in dogs?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 82 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Gabapentin in dogs · Medicines most reported with low sodium-potassium ratio (na:k ratio)