Leucocytosis after Gabapentin in dogs

The FDA has received 264 reports of leucocytosis in dogs after Gabapentin. That is 2.9% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

264Reports

84%Marked serious

7.6%Recovered

35%Died or euthanised

7 daysTypical onset

How soon it started

Same day

25 12%

1–2 days

40 20%

3–7 days

42 21%

1–4 weeks

42 21%

Over a month

54 27%

How the animals did

Recovered

20 7.6%

Still unwell when reported

111 42%

Died

31 12%

Euthanised

61 23%

Not known

41 16%

Problems reported at the same time

143 54%

142 54%

140 53%

126 48%

110 42%

98 37%

92 35%

80 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause leucocytosis in dogs?: 264 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

Leucocytosis after Selegiline (Anipryl) 54 reports · 1.3% of its reports
Leucocytosis after Trazodone 66 reports · 2.6% of its reports
Leucocytosis after Clomipramine (Clomicalm) 22 reports · 1.5% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with leucocytosis