Hypoproteinaemia after Gabapentin in dogs

The FDA has received 91 reports of hypoproteinaemia in dogs after Gabapentin. That is 1.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

91Reports

81%Marked serious

7.7%Recovered

44%Died or euthanised

11 daysTypical onset

How soon it started

Same day

11 15%

1–2 days

12 17%

3–7 days

10 14%

1–4 weeks

14 20%

Over a month

24 34%

How the animals did

Recovered

7 7.7%

Still unwell when reported

32 35%

Died

9 9.9%

Euthanised

31 34%

Not known

12 13%

Problems reported at the same time

55 60%

53 58%

46 51%

44 48%

40 44%

38 42%

34 37%

33 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause hypoproteinaemia in dogs?: 91 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoproteinaemia with similar medicines

Hypoproteinaemia after Trazodone 28 reports · 1.1% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with hypoproteinaemia