Hypercalcaemia after Gabapentin in dogs

55 reports to the FDA describe hypercalcaemia in dogs given Gabapentin. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports

78%Marked serious

9.1%Recovered

35%Died or euthanised

37 daysTypical onset

How soon it started

Same day

4 11%

1–2 days

2 5.7%

3–7 days

2 5.7%

1–4 weeks

8 23%

Over a month

19 54%

How the animals did

Recovered

4 7.3%

Recovered with lasting effects

1 1.8%

Still unwell when reported

21 38%

Died

2 3.6%

Euthanised

17 31%

Not known

10 18%

Problems reported at the same time

33 60%

28 51%

26 47%

25 45%

19 35%

18 33%

18 33%

16 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause hypercalcaemia in dogs?: 55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 37 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Gabapentin in dogs · Medicines most reported with hypercalcaemia