Gall bladder & bile duct disorder after Fuzapladib Sodium in dogs

The FDA has received 21 reports of gall bladder & bile duct disorder in dogs after Fuzapladib Sodium. That is 5.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports
86%Marked serious
0.0%Recovered
62%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
1 5.0%
1–2 days
6 30%
3–7 days
7 35%
1–4 weeks
2 10%
Over a month
4 20%

How the animals did

Still unwell when reported
8 38%
Died
4 19%
Euthanised
9 43%

Problems reported at the same time

13 62%
Elevated gamma-glutamyl transferase (ggt)
7 33%

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
1
8–11 years
11
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Fuzapladib Sodium cause gall bladder & bile duct disorder in dogs?
21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Gall bladder & bile duct disorder with similar medicines

All reported side effects of Fuzapladib Sodium in dogs · Medicines most reported with gall bladder & bile duct disorder