Decreased red blood cell count after Enrofloxacin (Baytril) in dogs

The FDA has received 44 reports of decreased red blood cell count in dogs after Enrofloxacin. That is 1.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

44Reports
95%Marked serious
2.3%Recovered
48%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
3 7.5%
1–2 days
6 15%
3–7 days
6 15%
1–4 weeks
11 28%
Over a month
14 35%

How the animals did

Recovered
1 2.3%
Still unwell when reported
11 25%
Died
8 18%
Euthanised
13 30%
Not known
11 25%

Problems reported at the same time

Liver problems
32 73%
Loss of appetite
23 52%
Leucocytosis
21 48%
Lethargy
20 45%
Low platelet count
20 45%
Decreased haemoglobin
20 45%
Death
20 45%
Kidney problems
19 43%

Age of the animals

Under 1 year
5
1–3 years
6
4–7 years
12
8–11 years
17
12+ years
4

About this medicine

Enrofloxacin treats bacterial infections.

Products with this ingredient include Baytril. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Enrofloxacin cause decreased red blood cell count in dogs?
44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased red blood cell count with similar medicines

All reported side effects of Enrofloxacin in dogs · Medicines most reported with decreased red blood cell count