Syncope after Enalapril in dogs

The FDA has received 25 reports of syncope in dogs after Enalapril. That is 1.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports

76%Marked serious

8.0%Recovered

24%Died or euthanised

96 daysTypical onset

How soon it started

Same day

2 14%

1–2 days

0 0.0%

3–7 days

1 7.1%

1–4 weeks

3 21%

Over a month

8 57%

How the animals did

Recovered

2 8.0%

Still unwell when reported

4 16%

Died

2 8.0%

Euthanised

4 16%

Not known

13 52%

Problems reported at the same time

5 20%

5 20%

4 16%

4 16%

3 12%

3 12%

3 12%

Didn't work as expected

3 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Enalapril cause syncope in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 96 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Syncope with similar medicines

Syncope after Melarsomine (Immiticide) 43 reports · 0.2% of its reports
Syncope after Furosemide 34 reports · 2.2% of its reports

All reported side effects of Enalapril in dogs · Medicines most reported with syncope