Low sodium-potassium ratio (na:k ratio) after Enalapril in dogs

28 reports to the FDA describe low sodium-potassium ratio (na:k ratio) in dogs given Enalapril. That is 1.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

28Reports

39%Marked serious

3.6%Recovered

7.1%Died or euthanised

145 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

1 5.0%

3–7 days

0 0.0%

1–4 weeks

2 10%

Over a month

17 85%

How the animals did

Recovered

1 3.6%

Still unwell when reported

8 29%

Euthanised

2 7.1%

Not known

17 61%

Problems reported at the same time

21 75%

7 25%

7 25%

6 21%

Hyponatremia

6 21%

Hypochloraemia

6 21%

Lipaemia

6 21%

Diarrhea

6 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Enalapril cause low sodium-potassium ratio (na:k ratio) in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 145 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low sodium-potassium ratio (na:k ratio) with similar medicines

Low sodium-potassium ratio (na:k ratio) after Desoxycorticosterone Pivalate 50 reports · 1.5% of its reports
Low sodium-potassium ratio (na:k ratio) after Furosemide 24 reports · 1.6% of its reports
Low sodium-potassium ratio (na:k ratio) after Ursodiol 21 reports · 2.9% of its reports

All reported side effects of Enalapril in dogs · Medicines most reported with low sodium-potassium ratio (na:k ratio)