Hypoproteinaemia after Distemper-parvo Vaccine in dogs

The FDA has received 76 reports of hypoproteinaemia in dogs after Distemper-parvo Vaccine. That is 1.2% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

76Reports

76%Marked serious

21%Recovered

36%Died or euthanised

11 daysTypical onset

How soon it started

Same day

13 18%

1–2 days

10 14%

3–7 days

11 15%

1–4 weeks

17 24%

Over a month

20 28%

How the animals did

Recovered

15 20%

Recovered with lasting effects

1 1.3%

Still unwell when reported

22 29%

Died

6 7.9%

Euthanised

21 28%

Not known

11 14%

Problems reported at the same time

42 55%

38 50%

38 50%

31 41%

30 39%

29 38%

27 36%

25 33%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Distemper-parvo Vaccine cause hypoproteinaemia in dogs?: 76 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoproteinaemia with similar medicines

Hypoproteinaemia after Rabies Vaccine 80 reports · 0.8% of its reports
Hypoproteinaemia after Bordetella Vaccine 81 reports · 0.9% of its reports
Hypoproteinaemia after Leptospirosis Vaccine 74 reports · 0.9% of its reports

All reported side effects of Distemper-parvo Vaccine in dogs · Medicines most reported with hypoproteinaemia