Paralysis after Carprofen (Rimadyl) in dogs

The FDA has received 190 reports of paralysis in dogs after Carprofen. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

190Reports

47%Marked serious

2.1%Recovered

52%Died or euthanised

4 daysTypical onset

How soon it started

Same day

13 15%

1–2 days

26 29%

3–7 days

12 13%

1–4 weeks

14 16%

Over a month

24 27%

How the animals did

Recovered

4 2.1%

Still unwell when reported

30 16%

Died

52 27%

Euthanised

47 25%

Not known

57 30%

Problems reported at the same time

102 54%

52 27%

42 22%

40 21%

31 16%

29 15%

27 14%

22 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause paralysis in dogs?: 190 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Paralysis with similar medicines

Paralysis after Grapiprant (Galliprant) 35 reports · 0.4% of its reports

All reported side effects of Carprofen in dogs · Medicines most reported with paralysis