Neoplasia after Carprofen (Rimadyl) in dogs

248 reports to the FDA describe neoplasia in dogs given Carprofen. That is 0.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

248Reports

22%Marked serious

0.4%Recovered

60%Died or euthanised

9 daysTypical onset

How soon it started

Same day

5 13%

1–2 days

7 18%

3–7 days

4 10%

1–4 weeks

6 15%

Over a month

18 45%

How the animals did

Recovered with lasting effects

1 0.4%

Still unwell when reported

20 8.1%

Died

130 52%

Euthanised

19 7.7%

Not known

78 31%

Problems reported at the same time

151 61%

92 37%

72 29%

69 28%

66 27%

60 24%

38 15%

36 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

115

12+ years

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause neoplasia in dogs?: 248 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neoplasia with similar medicines

Neoplasia after Deracoxib (Deramaxx) 61 reports · 0.6% of its reports
Neoplasia after Grapiprant (Galliprant) 40 reports · 0.5% of its reports
Neoplasia after Meloxicam (Metacam) 27 reports · 0.3% of its reports
Neoplasia after Firocoxib (Previcox) 23 reports · 0.3% of its reports

All reported side effects of Carprofen in dogs · Medicines most reported with neoplasia