Enlarged lymph node (localised) after Carprofen (Rimadyl) in dogs

The FDA has received 55 reports of enlarged lymph node (localised) in dogs after Carprofen. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports
85%Marked serious
5.5%Recovered
33%Died or euthanised
19 daysTypical onset
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How soon it started

Same day
8 15%
1–2 days
5 9.4%
3–7 days
6 11%
1–4 weeks
10 19%
Over a month
24 45%

How the animals did

Recovered
3 5.5%
Still unwell when reported
24 44%
Died
5 9.1%
Euthanised
13 24%
Not known
10 18%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
8
4–7 years
25
8–11 years
17
12+ years
3

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause enlarged lymph node (localised) in dogs?
55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Enlarged lymph node (localised) with similar medicines

All reported side effects of Carprofen in dogs · Medicines most reported with enlarged lymph node (localised)