Enlarged liver after Carprofen (Rimadyl) in dogs
80 reports to the FDA describe enlarged liver in dogs given Carprofen. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
80Reports
65%Marked serious
7.5%Recovered
35%Died or euthanised
5 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Carprofen relieves pain and inflammation from arthritis or after surgery.
Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.
Questions owners ask
- Can Carprofen cause enlarged liver in dogs?
- 80 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 5 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Enlarged liver with similar medicines
- Enlarged liver after Grapiprant (Galliprant) 25 reports · 0.3% of its reports
All reported side effects of Carprofen in dogs · Medicines most reported with enlarged liver