Decreased red blood cell count after Carprofen (Rimadyl) in dogs

The FDA has received 115 reports of decreased red blood cell count in dogs after Carprofen. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

115Reports
77%Marked serious
7.0%Recovered
37%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
9 11%
1–2 days
14 16%
3–7 days
10 12%
1–4 weeks
25 29%
Over a month
27 32%

How the animals did

Recovered
7 6.1%
Recovered with lasting effects
1 0.9%
Still unwell when reported
46 40%
Died
11 9.6%
Euthanised
31 27%
Not known
19 17%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
17
4–7 years
32
8–11 years
39
12+ years
21

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause decreased red blood cell count in dogs?
115 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased red blood cell count with similar medicines

All reported side effects of Carprofen in dogs · Medicines most reported with decreased red blood cell count