Ivermectin + Pyrantel (Heartgard Plus) side effects in King Charles Spaniels

83 FDA reports involve Ivermectin + Pyrantel in a King Charles Spaniel. These are the problems they describe.

Didn't work as expected
24 29%
Didn't stop worms
23 28%
Vomiting
23 28%
Digestive tract disorder
22 27%
Diarrhea
11 13%
Loss of appetite
7 8.4%
Lethargy
7 8.4%
Didn't prevent heartworm
4 4.8%
Loose stool
3 3.6%
Seizures
3 3.6%
Pacing
2 2.4%
Itching
2 2.4%

All reports for Ivermectin + Pyrantel in dogs