Ivermectin + Pyrantel (Heartgard Plus) side effects in King Charles Cavalier Spaniels

582 FDA reports involve Ivermectin + Pyrantel in a King Charles Cavalier Spaniel. These are the problems they describe.

Didn't stop worms
195 34%
Didn't work as expected
134 23%
Vomiting
102 18%
Digestive tract disorder
87 15%
Diarrhea
63 11%
Lethargy
42 7.2%
Didn't prevent heartworm
35 6.0%
Seizures
27 4.6%
Itching
20 3.4%
Loss of appetite
20 3.4%
Loose stool
14 2.4%
Death
12 2.1%

All reports for Ivermectin + Pyrantel in dogs