Ivermectin + Pyrantel (Heartgard Plus) side effects in Border Collies

1,450 FDA reports involve Ivermectin + Pyrantel in a Border Collie. These are the problems they describe.

Didn't prevent heartworm
626 43%
Didn't stop worms
316 22%
Didn't work as expected
300 21%
Digestive tract disorder
163 11%
Vomiting
147 10%
Cardiac disorder
130 9.0%
Diarrhea
90 6.2%
Lethargy
63 4.3%
Seizures
50 3.4%
Loss of appetite
42 2.9%
Overdose
21 1.4%
Itching
21 1.4%

All reports for Ivermectin + Pyrantel in dogs