Lymphopenia after Bordetella Vaccine in dogs

111 reports to the FDA describe lymphopenia in dogs given Bordetella Vaccine. That is 1.2% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

111Reports

84%Marked serious

13%Recovered

33%Died or euthanised

5 daysTypical onset

How soon it started

Same day

23 25%

1–2 days

12 13%

3–7 days

17 18%

1–4 weeks

21 23%

Over a month

20 22%

How the animals did

Recovered

14 13%

Still unwell when reported

49 44%

Died

9 8.1%

Euthanised

28 25%

Not known

11 9.9%

Problems reported at the same time

68 61%

66 59%

65 59%

57 51%

47 42%

42 38%

39 35%

39 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause lymphopenia in dogs?: 111 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphopenia with similar medicines

Lymphopenia after Rabies Vaccine 98 reports · 1.0% of its reports
Lymphopenia after Leptospirosis Vaccine 94 reports · 1.2% of its reports
Lymphopenia after Lyme Vaccine 26 reports · 0.4% of its reports
Lymphopenia after Distemper-parvo Vaccine 80 reports · 1.2% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with lymphopenia