Elevated creatine-kinase (ck) after Bordetella Vaccine in dogs

31 reports to the FDA describe elevated creatine-kinase (ck) in dogs given Bordetella Vaccine. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

31Reports

81%Marked serious

13%Recovered

26%Died or euthanised

6 daysTypical onset

How soon it started

Same day

9 32%

1–2 days

2 7.1%

3–7 days

4 14%

1–4 weeks

2 7.1%

Over a month

11 39%

How the animals did

Recovered

2 6.5%

Recovered with lasting effects

2 6.5%

Still unwell when reported

17 55%

Euthanised

8 26%

Not known

2 6.5%

Problems reported at the same time

23 74%

14 45%

13 42%

12 39%

11 35%

10 32%

9 29%

8 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause elevated creatine-kinase (ck) in dogs?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated creatine-kinase (ck) with similar medicines

Elevated creatine-kinase (ck) after Rabies Vaccine 29 reports · 0.3% of its reports
Elevated creatine-kinase (ck) after Leptospirosis Vaccine 27 reports · 0.3% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with elevated creatine-kinase (ck)