Elevated cholesterol (total) after Bordetella Vaccine in dogs

The FDA has received 43 reports of elevated cholesterol (total) in dogs after Bordetella Vaccine. That is 0.5% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports
81%Marked serious
16%Recovered
40%Died or euthanised
33 daysTypical onset
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How soon it started

Same day
8 25%
1–2 days
2 6.3%
3–7 days
2 6.3%
1–4 weeks
4 13%
Over a month
16 50%

How the animals did

Recovered
6 14%
Recovered with lasting effects
1 2.3%
Still unwell when reported
14 33%
Died
7 16%
Euthanised
10 23%
Not known
5 12%

Problems reported at the same time

Liver problems
33 77%
Lethargy
23 53%
Kidney problems
22 51%
Loss of appetite
20 47%
Hyperphosphataemia
17 40%
Death
17 40%
Vomiting
16 37%
Blood problems
15 35%

Age of the animals

Under 1 year
7
1–3 years
2
4–7 years
9
8–11 years
17
12+ years
8

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause elevated cholesterol (total) in dogs?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 33 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with elevated cholesterol (total)