Dysphoria after Robenacoxib (Onsior) in cats

The FDA has received 95 reports of dysphoria in cats after Robenacoxib. That is 2.9% of all reports for this medicine, compared with 0.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

95Reports

29%Marked serious

36%Recovered

5.3%Died or euthanised

Same dayTypical onset

How soon it started

Same day

56 61%

1–2 days

28 30%

3–7 days

3 3.3%

1–4 weeks

1 1.1%

Over a month

4 4.3%

How the animals did

Recovered

34 36%

Still unwell when reported

41 43%

Died

4 4.2%

Euthanised

1 1.1%

Not known

15 16%

Problems reported at the same time

Loss of appetite

35 37%

Behaviour change

26 27%

Restlessness or agitation

25 26%

24 25%

20 21%

17 18%

12 13%

11 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Robenacoxib relieves pain and inflammation (short courses).

Products with this ingredient include Onsior. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Robenacoxib cause dysphoria in cats?: 95 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dysphoria with similar medicines

Dysphoria after Meloxicam (Metacam) 28 reports · 0.8% of its reports

All reported side effects of Robenacoxib in cats · Medicines most reported with dysphoria