Lethargy after Polysulfated Glycosaminoglycan in cats

The FDA has received 80 reports of lethargy in cats after Polysulfated Glycosaminoglycan. That is 19% of all reports for this medicine, compared with 14% across reports for all cat medicines.

80Reports
35%Marked serious
26%Recovered
20%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
19 40%
1–2 days
7 15%
3–7 days
3 6.4%
1–4 weeks
10 21%
Over a month
8 17%

How the animals did

Recovered
21 26%
Still unwell when reported
10 13%
Died
6 7.5%
Euthanised
10 13%
Not known
33 41%

Problems reported at the same time

29 36%
16 20%
Dehydration
6 7.5%

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
3
8–11 years
13
12+ years
59

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause lethargy in cats?
80 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in cats · Medicines most reported with lethargy