Elevated globulins after Mirtazapine (Mirataz) in cats

The FDA has received 23 reports of elevated globulins in cats after Mirtazapine. That is 1.2% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

23Reports

78%Marked serious

17%Recovered

48%Died or euthanised

9 daysTypical onset

How soon it started

Same day

5 25%

1–2 days

4 20%

3–7 days

1 5.0%

1–4 weeks

7 35%

Over a month

3 15%

How the animals did

Recovered

4 17%

Still unwell when reported

5 22%

Died

1 4.3%

Euthanised

10 43%

Not known

3 13%

Problems reported at the same time

18 78%

12 52%

11 48%

11 48%

9 39%

8 35%

8 35%

8 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Mirtazapine stimulates appetite (cats: ointment applied to the ear).

Products with this ingredient include Mirataz. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Mirtazapine cause elevated globulins in cats?: 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

Elevated globulins after Maropitant (Cerenia) 73 reports · 1.9% of its reports

All reported side effects of Mirtazapine in cats · Medicines most reported with elevated globulins