Diarrhea after Mirtazapine (Mirataz) in cats

The FDA has received 124 reports of diarrhea in cats after Mirtazapine. That is 6.6% of all reports for this medicine, compared with 5.1% across reports for all cat medicines.

124Reports

65%Marked serious

21%Recovered

23%Died or euthanised

4 daysTypical onset

How soon it started

Same day

24 21%

1–2 days

21 19%

3–7 days

19 17%

1–4 weeks

22 19%

Over a month

27 24%

How the animals did

Recovered

26 21%

Still unwell when reported

39 31%

Died

9 7.3%

Euthanised

19 15%

Not known

31 25%

Problems reported at the same time

60 48%

49 40%

32 26%

27 22%

23 19%

16 13%

15 12%

14 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Mirtazapine stimulates appetite (cats: ointment applied to the ear).

Products with this ingredient include Mirataz. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Mirtazapine cause diarrhea in cats?: 124 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

Diarrhea after Maropitant (Cerenia) 340 reports · 8.8% of its reports
Diarrhea after Capromorelin (Entyce) 38 reports · 4.6% of its reports

All reported side effects of Mirtazapine in cats · Medicines most reported with diarrhea