Hypotension after Midazolam in cats

The FDA has received 26 reports of hypotension in cats after Midazolam. That is 3.5% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

26Reports

69%Marked serious

54%Recovered

31%Died or euthanised

Same dayTypical onset

How soon it started

Same day

13 65%

1–2 days

4 20%

3–7 days

1 5.0%

1–4 weeks

2 10%

Over a month

0 0.0%

How the animals did

Recovered

14 54%

Still unwell when reported

3 12%

Died

5 19%

Euthanised

3 12%

Not known

1 3.8%

Problems reported at the same time

10 38%

8 31%

6 23%

5 19%

5 19%

4 15%

3 12%

3 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause hypotension in cats?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypotension with similar medicines

Hypotension after Ketamine 39 reports · 1.2% of its reports
Hypotension after Butorphanol 41 reports · 1.8% of its reports
Hypotension after Isoflurane 70 reports · 3.4% of its reports
Hypotension after Propofol 49 reports · 4.2% of its reports
Hypotension after Alfaxalone 27 reports · 5.7% of its reports
Hypotension after Ampicillin 23 reports · 7.6% of its reports

All reported side effects of Midazolam in cats · Medicines most reported with hypotension