Decreased body temperature after Midazolam in cats

The FDA has received 20 reports of decreased body temperature in cats after Midazolam. That is 2.7% of all reports for this medicine, compared with 0.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

20Reports

60%Marked serious

20%Recovered

40%Died or euthanised

Same dayTypical onset

How soon it started

Same day

15 88%

1–2 days

1 5.9%

3–7 days

0 0.0%

1–4 weeks

1 5.9%

Over a month

0 0.0%

How the animals did

Recovered

4 20%

Still unwell when reported

4 20%

Died

3 15%

Euthanised

5 25%

Not known

4 20%

Problems reported at the same time

8 40%

7 35%

5 25%

5 25%

4 20%

4 20%

3 15%

3 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause decreased body temperature in cats?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased body temperature with similar medicines

Decreased body temperature after Ketamine 23 reports · 0.7% of its reports
Decreased body temperature after Butorphanol 22 reports · 1.0% of its reports
Decreased body temperature after Isoflurane 46 reports · 2.3% of its reports
Decreased body temperature after Propofol 20 reports · 1.7% of its reports

All reported side effects of Midazolam in cats · Medicines most reported with decreased body temperature