Neutrophilia after Methylprednisolone in cats

The FDA has received 42 reports of neutrophilia in cats after Methylprednisolone. That is 2.6% of all reports for this medicine, compared with 0.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

42Reports

48%Marked serious

12%Recovered

29%Died or euthanised

4 daysTypical onset

How soon it started

Same day

5 16%

1–2 days

10 32%

3–7 days

2 6.5%

1–4 weeks

7 23%

Over a month

7 23%

How the animals did

Recovered

5 12%

Still unwell when reported

18 43%

Died

4 9.5%

Euthanised

8 19%

Not known

7 17%

Problems reported at the same time

24 57%

19 45%

17 40%

12 29%

12 29%

12 29%

11 26%

10 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Methylprednisolone cause neutrophilia in cats?: 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

Neutrophilia after Ketamine 23 reports · 0.7% of its reports
Neutrophilia after Butorphanol 29 reports · 1.3% of its reports
Neutrophilia after Isoflurane 28 reports · 1.4% of its reports
Neutrophilia after Vitamin B12 20 reports · 5.2% of its reports

All reported side effects of Methylprednisolone in cats · Medicines most reported with neutrophilia