Low thyroxine (t4) after Methimazole in cats

34 reports to the FDA describe low thyroxine (t4) in cats given Methimazole. That is 1.9% of all reports for this medicine, compared with 0.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

34Reports

44%Marked serious

12%Recovered

8.8%Died or euthanised

35 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

0 0.0%

3–7 days

1 3.2%

1–4 weeks

11 35%

Over a month

19 61%

How the animals did

Recovered

4 12%

Still unwell when reported

4 12%

Died

2 5.9%

Euthanised

1 2.9%

Not known

23 68%

Problems reported at the same time

13 38%

12 35%

11 32%

8 24%

8 24%

6 18%

6 18%

Didn't work as expected

5 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Methimazole treats an overactive thyroid in cats.

Questions owners ask

Can Methimazole cause low thyroxine (t4) in cats?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 35 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Methimazole in cats · Medicines most reported with low thyroxine (t4)