Third eyelid protrusion after Maropitant (Cerenia) in cats

47 reports to the FDA describe third eyelid protrusion in cats given Maropitant. That is 1.2% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

47Reports

94%Marked serious

21%Recovered

30%Died or euthanised

2 daysTypical onset

How soon it started

Same day

10 22%

1–2 days

14 31%

3–7 days

4 8.9%

1–4 weeks

9 20%

Over a month

8 18%

How the animals did

Recovered

10 21%

Still unwell when reported

11 23%

Died

3 6.4%

Euthanised

11 23%

Not known

12 26%

Problems reported at the same time

27 57%

26 55%

14 30%

13 28%

11 23%

10 21%

8 17%

8 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause third eyelid protrusion in cats?: 47 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Third eyelid protrusion with similar medicines

Third eyelid protrusion after Capromorelin (Entyce) 28 reports · 3.4% of its reports

All reported side effects of Maropitant in cats · Medicines most reported with third eyelid protrusion