Not sleeping after Maropitant (Cerenia) in cats

The FDA has received 63 reports of not sleeping in cats after Maropitant. That is 1.6% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

63Reports

21%Marked serious

29%Recovered

7.9%Died or euthanised

Same dayTypical onset

How soon it started

Same day

37 60%

1–2 days

20 32%

3–7 days

1 1.6%

1–4 weeks

3 4.8%

Over a month

1 1.6%

How the animals did

Recovered

18 29%

Still unwell when reported

24 38%

Euthanised

5 7.9%

Not known

16 25%

Problems reported at the same time

Restlessness or agitation

34 54%

30 48%

22 35%

18 29%

12 19%

9 14%

9 14%

8 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause not sleeping in cats?: 63 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not sleeping with similar medicines

Not sleeping after Mirtazapine (Mirataz) 20 reports · 1.1% of its reports

All reported side effects of Maropitant in cats · Medicines most reported with not sleeping