Liver problems after Maropitant (Cerenia) in cats

331 reports to the FDA describe liver problems in cats given Maropitant. That is 8.6% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

331Reports

79%Marked serious

10%Recovered

40%Died or euthanised

2 daysTypical onset

How soon it started

Same day

83 30%

1–2 days

67 24%

3–7 days

45 16%

1–4 weeks

39 14%

Over a month

43 16%

How the animals did

Recovered

34 10%

Still unwell when reported

116 35%

Died

54 16%

Euthanised

77 23%

Not known

50 15%

Problems reported at the same time

200 60%

143 43%

139 42%

128 39%

111 34%

80 24%

80 24%

77 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

105

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause liver problems in cats?: 331 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Mirtazapine (Mirataz) 126 reports · 6.7% of its reports
Liver problems after Capromorelin (Entyce) 46 reports · 5.6% of its reports

All reported side effects of Maropitant in cats · Medicines most reported with liver problems