Kidney problems after Lufenuron in cats

The FDA has received 45 reports of kidney problems in cats after Lufenuron. That is 4.1% of all reports for this medicine, compared with 4.5% across reports for all cat medicines.

45Reports

4.4%Marked serious

2.2%Recovered

24%Died or euthanised

–Typical onset

How the animals did

Recovered with lasting effects

1 2.2%

Died

10 22%

Euthanised

1 2.2%

Not known

33 73%

Problems reported at the same time

23 51%

16 36%

13 29%

11 24%

8 18%

7 16%

Hyperglycaemia

6 13%

Pr-liver, lesion(s)

5 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lufenuron stops flea eggs from developing.

Questions owners ask

Can Lufenuron cause kidney problems in cats?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Spinosad (Comfortis) 108 reports · 0.9% of its reports
Kidney problems after Nitenpyram (Capstar) 57 reports · 0.7% of its reports
Kidney problems after Imidacloprid + Moxidectin (Advantage Multi) 92 reports · 1.1% of its reports

All reported side effects of Lufenuron in cats · Medicines most reported with kidney problems