Fever after Lufenuron in cats

80 reports to the FDA describe fever in cats given Lufenuron. That is 7.2% of all reports for this medicine, compared with 3.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

80Reports

8.8%Marked serious

3.8%Recovered

5.0%Died or euthanised

–Typical onset

How the animals did

Recovered

3 3.8%

Still unwell when reported

3 3.8%

Died

3 3.8%

Euthanised

1 1.3%

Not known

70 88%

Problems reported at the same time

Lethargy

50 63%

Loss of appetite

44 55%

Injection site reaction

20 25%

17 21%

11 14%

10 13%

9 11%

8 10%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lufenuron stops flea eggs from developing.

Questions owners ask

Can Lufenuron cause fever in cats?: 80 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Spinosad (Comfortis) 78 reports · 0.7% of its reports
Fever after Nitenpyram (Capstar) 239 reports · 2.7% of its reports
Fever after Imidacloprid + Moxidectin (Advantage Multi) 182 reports · 2.2% of its reports

All reported side effects of Lufenuron in cats · Medicines most reported with fever