Third eyelid protrusion after Isoflurane in cats

24 reports to the FDA describe third eyelid protrusion in cats given Isoflurane. That is 1.2% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

24Reports
46%Marked serious
38%Recovered
21%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
13 57%
1–2 days
8 35%
3–7 days
1 4.3%
1–4 weeks
1 4.3%
Over a month
0 0.0%

How the animals did

Recovered
7 29%
Recovered with lasting effects
2 8.3%
Still unwell when reported
5 21%
Died
2 8.3%
Euthanised
3 13%
Not known
5 21%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
4
4–7 years
5
8–11 years
6
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause third eyelid protrusion in cats?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Third eyelid protrusion with similar medicines

All reported side effects of Isoflurane in cats · Medicines most reported with third eyelid protrusion