Elevated globulins after Gabapentin in cats

The FDA has received 36 reports of elevated globulins in cats after Gabapentin. That is 1.8% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

36Reports

78%Marked serious

11%Recovered

22%Died or euthanised

13 daysTypical onset

How soon it started

Same day

5 16%

1–2 days

6 19%

3–7 days

3 9.4%

1–4 weeks

8 25%

Over a month

10 31%

How the animals did

Recovered

4 11%

Still unwell when reported

13 36%

Died

5 14%

Euthanised

3 8.3%

Not known

11 31%

Problems reported at the same time

Loss of appetite

22 61%

Lethargy

21 58%

Kidney problems

15 42%

Hyperproteinaemia

11 31%

Weight loss

10 28%

Elevated symmetrical dimethylarginine (sdma)

10 28%

Liver problems

9 25%

Blood problems

8 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause elevated globulins in cats?: 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Gabapentin in cats · Medicines most reported with elevated globulins