Skin rash or irritation after Flumethrin + Imidacloprid (Seresto) in cats

The FDA has received 43 reports of skin rash or irritation in cats after Flumethrin + Imidacloprid. That is 6.4% of all reports for this medicine, compared with 2.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

43Reports
84%Marked serious
26%Recovered
12%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
1 3.1%
1–2 days
1 3.1%
3–7 days
6 19%
1–4 weeks
11 34%
Over a month
13 41%

How the animals did

Recovered
11 26%
Still unwell when reported
5 12%
Died
2 4.7%
Euthanised
3 7.0%
Not known
22 51%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
16
4–7 years
12
8–11 years
7
12+ years
7

About this medicine

Imidacloprid kills fleas (spot-on or collar).

Products with this combination include Seresto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Flumethrin + Imidacloprid cause skin rash or irritation in cats?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

All reported side effects of Flumethrin + Imidacloprid in cats · Medicines most reported with skin rash or irritation