Lethargy after Dexamethasone in cats

258 reports to the FDA describe lethargy in cats given Dexamethasone. That is 34% of all reports for this medicine, compared with 14% across reports for all cat medicines, so it is reported unusually often with this medicine.

258Reports
70%Marked serious
22%Recovered
34%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
91 37%
1–2 days
57 23%
3–7 days
33 13%
1–4 weeks
46 19%
Over a month
18 7.3%

How the animals did

Recovered
55 21%
Recovered with lasting effects
1 0.4%
Still unwell when reported
90 35%
Died
41 16%
Euthanised
47 18%
Not known
24 9.3%

Problems reported at the same time

Age of the animals

Under 1 year
30
1–3 years
58
4–7 years
58
8–11 years
55
12+ years
52

About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Dexamethasone cause lethargy in cats?
258 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Dexamethasone in cats · Medicines most reported with lethargy