Liver problems after Dexamethasone + Neomycin + Thiabendazole in cats

The FDA has received 115 reports of liver problems in cats after Dexamethasone + Neomycin + Thiabendazole. That is 14% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

115Reports

50%Marked serious

11%Recovered

15%Died or euthanised

13 daysTypical onset

How soon it started

Same day

8 8.8%

1–2 days

7 7.7%

3–7 days

9 9.9%

1–4 weeks

57 63%

Over a month

10 11%

How the animals did

Recovered

13 11%

Still unwell when reported

28 24%

Died

4 3.5%

Euthanised

13 11%

Not known

57 50%

Problems reported at the same time

75 65%

49 43%

29 25%

28 24%

22 19%

17 15%

17 15%

14 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Dexamethasone + Neomycin + Thiabendazole cause liver problems in cats?: 115 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Prednisolone 89 reports · 7.2% of its reports
Liver problems after Prednisone 45 reports · 5.1% of its reports
Liver problems after Dexamethasone 93 reports · 12% of its reports

All reported side effects of Dexamethasone + Neomycin + Thiabendazole in cats · Medicines most reported with liver problems