Foaming at the mouth after Cyclosporine (Atopica) in cats

105 reports to the FDA describe foaming at the mouth in cats given Cyclosporine. That is 3.5% of all reports for this medicine, compared with 1.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

105Reports

18%Marked serious

61%Recovered

1.9%Died or euthanised

Same dayTypical onset

How soon it started

Same day

57 63%

1–2 days

2 2.2%

3–7 days

4 4.4%

1–4 weeks

10 11%

Over a month

17 19%

How the animals did

Recovered

64 61%

Still unwell when reported

13 12%

Died

1 1.0%

Euthanised

1 1.0%

Not known

26 25%

Problems reported at the same time

27 26%

14 13%

14 13%

8 7.6%

8 7.6%

7 6.7%

6 5.7%

Restlessness or agitation

5 4.8%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause foaming at the mouth in cats?: 105 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Cyclosporine in cats · Medicines most reported with foaming at the mouth