Dehydration after Capromorelin (Entyce) in cats

The FDA has received 35 reports of dehydration in cats after Capromorelin. That is 4.3% of all reports for this medicine, compared with 2.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

35Reports

80%Marked serious

5.7%Recovered

23%Died or euthanised

10 daysTypical onset

How soon it started

Same day

3 11%

1–2 days

1 3.7%

3–7 days

8 30%

1–4 weeks

4 15%

Over a month

11 41%

How the animals did

Recovered

2 5.7%

Still unwell when reported

14 40%

Died

2 5.7%

Euthanised

6 17%

Not known

11 31%

Problems reported at the same time

26 74%

19 54%

13 37%

13 37%

11 31%

10 29%

9 26%

9 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause dehydration in cats?: 35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Maropitant (Cerenia) 292 reports · 7.6% of its reports
Dehydration after Mirtazapine (Mirataz) 99 reports · 5.3% of its reports

All reported side effects of Capromorelin in cats · Medicines most reported with dehydration