Bradycardia after Capromorelin (Entyce) in cats

The FDA has received 121 reports of bradycardia in cats after Capromorelin. That is 15% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

121Reports

57%Marked serious

57%Recovered

6.6%Died or euthanised

Same dayTypical onset

How soon it started

Same day

83 69%

1–2 days

19 16%

3–7 days

4 3.3%

1–4 weeks

5 4.2%

Over a month

9 7.5%

How the animals did

Recovered

69 57%

Still unwell when reported

23 19%

Died

1 0.8%

Euthanised

7 5.8%

Not known

21 17%

Problems reported at the same time

57 47%

38 31%

16 13%

13 11%

11 9.1%

Dull

11 9.1%

Breathing problems

10 8.3%

Unresponsive

9 7.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause bradycardia in cats?: 121 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Bradycardia with similar medicines

Bradycardia after Maropitant (Cerenia) 105 reports · 2.7% of its reports

All reported side effects of Capromorelin in cats · Medicines most reported with bradycardia