Hypercalcaemia after Bexagliflozin (Bexacat) in cats

108 reports to the FDA describe hypercalcaemia in cats given Bexagliflozin. That is 2.7% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

108Reports
31%Marked serious
1.9%Recovered
5.6%Died or euthanised
49 daysTypical onset
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How soon it started

Same day
6 6.5%
1–2 days
6 6.5%
3–7 days
8 8.6%
1–4 weeks
19 20%
Over a month
54 58%

How the animals did

Recovered
2 1.9%
Still unwell when reported
55 51%
Died
1 0.9%
Euthanised
5 4.6%
Not known
45 42%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
7
8–11 years
45
12+ years
49

About this medicine

Bexagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Bexacat. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bexagliflozin cause hypercalcaemia in cats?
108 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 49 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypercalcaemia with similar medicines

All reported side effects of Bexagliflozin in cats · Medicines most reported with hypercalcaemia