Swelling after Amoxicillin + Clavulanate (Clavamox) in cats

The FDA has received 86 reports of swelling in cats after Amoxicillin + Clavulanate. That is 3.6% of all reports for this medicine, compared with 1.9% across reports for all cat medicines, so it is reported unusually often with this medicine.

86Reports

22%Marked serious

13%Recovered

35%Died or euthanised

2 daysTypical onset

How soon it started

Same day

10 27%

1–2 days

9 24%

3–7 days

7 19%

1–4 weeks

9 24%

Over a month

2 5.4%

How the animals did

Recovered

11 13%

Still unwell when reported

15 17%

Died

25 29%

Euthanised

5 5.8%

Not known

30 35%

Problems reported at the same time

30 35%

28 33%

25 29%

23 27%

20 23%

Abnormal radiograph finding

15 17%

Allergic reaction

13 15%

Blood problems

12 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause swelling in cats?: 86 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Cefovecin (Convenia) 456 reports · 5.3% of its reports
Swelling after Enrofloxacin (Baytril) 58 reports · 3.7% of its reports

All reported side effects of Amoxicillin + Clavulanate in cats · Medicines most reported with swelling